The BSE Sensex fell over 90 points in opening trade on selling by foreign funds and retail investors, triggered by a weak trend in the Asian region.
The 30-share index of the Bombay Stock Exchange fell by 90.36 points, or 0.44 per cent, to 20,423.49. The Sensex had gained 15.60 points in the previous session.
Stocks of IT, consumer durables, realty, capital goods and oil and gas sectors led the fall.
The 50-share National Stock Exchange index Nifty declined by 26.10 points, or 0.43 per cent, to 6,063.40.
Brokers said trading sentiment dampened largely in line with a weak trend in the Asian region following another global sell-off caused by anxieties over emerging markets and further disappointing manufacturing data from China.
In the Asian region, the Japan's Nikkei down 1.24 per cent in early trade on Monday while Hong Kong markets were closed for public holiday. The US Dow Jones Industrial Average ended 0.94 per cent lower in Friday's trade.